About the Centre
The Centre for Predictive Human Model Systems is India's first Centre dedicated to enable a shift in science by focusing on 21st century new-approach methodologies instead of animal models for research. The Centre aims to prioritise investment in human-based, non-animal methodologies in life sciences research in India. With the aim of breaking silos and forging partnerships, the Centre is a joint initiative by Atal Incubation Centre - Centre for Cellular and Molecular Biology (AIC - CCMB) and Humane Society International India (HSI/India).
Why was the Centre created?
Basic and clinical research has been based on various animal models such as mice, rats, monkeys, fish, worms, flies etc. While the genome of many of these animal models find similarities with humans, it is increasingly emerging the differences between the species contribute to the complexities and subtleties of the human biology. With advances in toxicogenomics, bioinformatics, cell and molecular biology, and computational tools, the global scientific community is gearing towards developing model systems that are relevant to humans. These systems can be further used to develop predictive models to understand human development, disease biology, and toxicity responses. The Centre aims to promote the development and application of human-relevant methodologies and establish India as a key player in this field.