AIC-CCMB

Research Associate Sci-Com

Organoids: More than tissue culture and not less than animal models!

Organoids: More than tissue culture and not less than animal models! Karthic A SIIPL, Pune Inventing or discovering a new medicinal drug takes an average of 10 years from mind to market. It is due to the extensive regulation involved in assessing the safety and efficacy of any new active pharmaceutical ingredient in its administrable …

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Artwork

The Human Angle: Art Inspired by Human Relevant Research Organoids Polaroids Contest 1st Prize – Sri Harsha Paladugu, IISc Bangalore 2nd Prize – Sukanya Gayan, Savitribai Phule Pune University Dr. Bharadwaja Vadloori, Oncoseek Bio Pvt. Ltd. Marthe Priouret, Institut for Molecular Biotechnologie (IMBA), Vienna Ami Mehta, IIT-Bombay & Monash Research Academy The Human Angle: Art …

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Vast Potentials of Microphysiological Systems

Vast Potentials of Microphysiological Systems Sudeepa Nandi Tata Institute of Fundamental Research, Mumbai With a growing need in the biomedical field, it is imminent to find the best of model systems to address basic and translational questions. For decades, 2D cultures have been used immensely, for disease modelling studies to test drugs for diseases. However, …

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An Original 3D Culture Model: Human Pancreatic Cancerous Organoids Generated in Liquid Pearls

An Original 3D Culture Model: Human Pancreatic Cancerous Organoids Generated in Liquid Pearls Christian D. Muller Dr. ès Sciences, Ph.D. CSO & Founder, PearlBioSystem  In recent years, interest in medicinal Cannabis sativa L. has been rising, as legislation is moving in the right direction. In our laboratory we compared different cannabinoid extraction methods to identify …

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Reverse Engineering Biology: The Dawn of Microphysiological Systems

Reverse Engineering Biology: The Dawn of Microphysiological Systems Sri Harsha Paladugu Reverse engineering or backward engineering is a way to understand complex systems (such as machines, software, and protocols) and repurpose them for better applications. This process became popular during the Second World War and the Cold War, wherein each nation tried to copy the …

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Microphysiological systems and their applications at InSphero

Microphysiological systems, which includes spheroids and microfluidic systems, enable  studies to understand the underlying mechanisms of diseases and promises to accelerate  the development of drugs and predict how individual patients will respond to said drugs. InSphero’s Akura™ Flow represents a plug & play concept where 3D spheroids representing  various or individual organs are loaded into …

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Human-induced Pluripotent Cell (hiPSC) isolation and formation of organoids

“Human-induced Pluripotent Cell (hiPSC) isolation and formation of organoids” Dr Mamta Mishra, M.Sc., M.Phil., Ph.D., Senior Research Scientist, Jai Research Foundation, Gujarat, India Induced pluripotent stem cells are artificial stem cells and do not exist naturally. Instead, they are generated or reprogrammed from somatic cells by ectopic expression of pluripotency factors or specific transcription factors …

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